Research Archives - Lewy Body Dementia Association

Gut Health and Parkinson’s Disease Dementia: A Hidden Connection?

July 1, 2025 Is there a connection between bacteria in the mouth and gut and the development of dementia in Parkinson’s disease? New research may shed light. Cognitive decline and […]

Testing a Caregiver Intervention: Initial Findings from the PERSEVERE Study

June 3, 2025 Lewy Body dementia (LBD) includes Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB). As the disease progresses, people with LBD need assistance that is not […]

New RewinD-LB Trial Results Show Promise

March 19, 2025 Earlier this month, CervoMed Pharmaceuticals reported data from an open-label extension phase of the RewinD-LB trial suggesting that the study drug, neflamapimod, may slow cognitive decline in […]

New imaging study reveals that energy use in the brain begins to decline early in DLB

January 5, 2025 A new research paper from Mayo Clinic and the Karolinska Institutet suggests that the brain’s energy use levels decline measurably early in the course of the disease. […]

SHIMMER Trial Reports Positive Results

December 18, 2024 This week Cognition Therapeutics reported encouraging topline results from their Phase 2 clinical trial of CT1812, an investigational drug being studied in people with dementia with Lewy […]

Trial Results – Experimental Drug Shows Promising Results in Phase 2 Trial

November 14, 2024 Clinical trial results reported at a recent scientific conference suggest that the drug nilotinib may improve outcomes in people with dementia with Lewy bodies (DLB). Nilotinib is […]

LBD Clinical Trials around the World

November 5, 2024 2024 has been an exciting year for clinical trials for people with Lewy body dementia (LBD). Over the past year, you have heard a lot from the […]

Does kidney injury increase risk for LBD?

September 26, 2024 A new study published in the medical research journal Neurology suggests that sudden worsening of kidney function (referred to as “acute kidney injury”) may nearly double the […]

Special Research Topic: Right of Withdrawal – What Research Participants Need to Know

September 04, 2024 Clinical trials are the key to unlocking future treatments and preventive strategies for Lewy body dementia (LBD). Only by testing new medications in controlled experiments, called trials, […]

Eye on Prevention: Clues from Prostate Therapy

August 05, 2024 According to new research from the University of Iowa, medications used for prostate enlargement may provide clues to future strategies to prevent dementia with Lewy bodies (DLB). […]

New Research Suggests Skin Test Can Detect Dementia with Lewy Bodies

May 29, 2024 Many people who have dementia with Lewy bodies (DLB) experience delay and difficulty with receiving an accurate diagnosis, often seeing multiple specialists before being correctly diagnosed. In […]

New Research Supports Nuplazid (Pimavanserin) Use in Parkinson’s Disease Dementia

March 18, 2024 Hallucinations and delusions (also called psychosis) are prominent features of Lewy body dementia (LBD), occurring in both dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD). […]

The U.S. Based DIAMOND Lewy™ Management Toolkit

Originally developed in the UK for dissemination via the National Health Service, the Diamond Lewy™ Management Toolkit provides a comprehensive overview of the management of the complex symptoms of Lewy body […]

Advancing the Science: New Research Frameworks Proposed for the Biology of Dementia with Lewy Bodies and/or Parkinson’s Disease

Two articles published on January 22, 2024, in The Lancet Neurology journal are proposing complementary but different research frameworks for biological definitions of Lewy body disease, a label reflecting the […]

Men are at greater risk for Lewy body dementia than women, but why? New study seeks answers

Ece Bayram, MD, PhD. Researcher from the Lewy Body Dementia Association’s Research Center of Excellence at University of California San Diego December 12, 2023 Research suggests men have a higher […]

Research Update: Digging Deeper into Caregiver Strain—LBD Care Partners Report Elevated Levels of High Blood Pressure, Depression, Chronic Back Pain, and Arthritis

November 3, 2023 Caring for a person with Lewy body dementia (LBD) can be very difficult, For example, cognitive changes in LBD are more likely to involve executive function and […]