Biomarkers: The Pathway to Earlier LBD Diagnosis and Better Treatments

In LBD clinical research, scientists use tests that measure both the symptoms of a disease and also what biological changes are underway. Those tests that detect the presence or progression […]
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Is Pure Autonomic Failure a Warning Sign of LBD?

Many people with one specific form of LBD, called dementia with Lewy bodies or DLB, develop problems with their autonomic nervous system. This is the part of the nervous system […]
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Loss of Smell in Parkinson’s Disease Increases Risk of Dementia

The loss of smell is a common symptom in LBD, Parkinson’s disease and even Alzheimer’s disease. New research suggests the loss of smell in Parkinson’s disease (PD) may help predict […]
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HOT NEWS: Preliminary LBD Clinical Trial Results Announced

This week Axovant Sciences released preliminary results for one of its LBD clinical trials of an experimental medication, nelotanserin. The first eleven people with LBD have completed the Phase 2 […]
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LBD Duration Shortens with Co-existing Alzheimer’s Disease

The rate of progression in Lewy body dementia (LBD) is hard to predict at the time of diagnosis. New research indicates the presence of a second neurodegenerative disease process, Alzheimer’s […]
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LBD: State of the Science

We are entering an era of unprecedented opportunity for understanding and treating Lewy body dementia (LBD). Our newest white paper, Lewy Body Dementia: The State of the Science provides the […]
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Treatment

Goals of Care | First-Line Medications | Other Drugs to Avoid Download this article as a PDF The importance of early treatment is supported by recent data suggesting that patients […]
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Symptoms Differ in Alzheimer’s when Lewy Bodies are Present

Lewy body pathology (presence of Lewy bodies in the brain)  is found in up to 50% of cases of late-onset Alzheimer’s disease, which can make it challenging for physicians to […]
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Qualitative EEG shows promise in Identifying Mild DLB

Dementia is often preceded by an earlier phase called mild cognitive impairment (MCI), where an individual is still able to live independently, but notices changes in at least one area […]
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Daytime Sleepiness is More Common in Dementia with Lewy Bodies than Alzheimer’s

Drowsiness and daytime sleepiness (despite getting adequate sleep the night before) are often described by individuals with dementia with Lewy bodies (DLB) and their caregivers. This is reported even in […]
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Long-Term Caregiving May Shorten Life Up to Eight Years

By Carol Bradley Bursack A new study by Ohio State University in conjunction with the National Institute on Aging has shown that adult children caring for their parents, as well […]
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Adult Day Service Boosts Beneficial Stress Hormone in Caregivers

A new study reveals family caregivers have an increase in the beneficial stress hormone DHEA-S on days when they use an adult day service for their relatives with dementia. DHEA-S […]
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Can Exercise Help Older Women at Risk for Dementia?

Regular aerobic workouts increase the size of the brain’s memory area in older women and may help slow the progression of dementia, according to a small new study. It included […]
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Ask the Expert: Why Do Many People with LBD Respond Poorly to Surgery?

By Farzana Pervin, M.D. and Carol F Lippa, M.D., Drexel University College of Medicine Need to make a decision on surgery for someone with Lewy body dementia (LBD)? Family members […]
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Ask the Expert: What is the Role of the Geriatric Psychiatrist in LBD?

By Daniel Weintraub, MD, Ian McKeith, MD, FRCPsych, Peter Rabins, MD, MPH Care of the cognitive, psychiatric and neurologic features of Lewy body dementias (LBD), including dementia with Lewy bodies […]
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Longevity May be Impacted by Orthostatic Hypotension in LBD

The autonomic nervous system regulates functions in the body that are involuntary, such as blood pressure and digestion. This system malfunctions in LBD, causing problems with blood pressure regulation, urinary […]
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MCI with Visual Spatial or Attention Deficits Progresses to DLB over Alzheimer’s

A study by Tanis Ferman, PhD and colleagues at Mayo Clinic assessed the progression from mild cognitive impairment (MCI) to different forms of dementia. 337 people with mild cognitive impairment […]
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Sleep Disorder Increases Odds of DLB by Five Times Over Alzheimer’s

REM sleep behavior disorder (RBD) is a condition that causes a person to physically act out their dreams and is a common in Lewy body dementia (LBD). RBD is a […]
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Early Visual Hallucinations Greatly Increase Odds of LBD Over Alzheimer’s

Visual hallucinations are a core feature of dementia with Lewy bodies, occurring in 32 to 85 percent of autopsy-confirmed cases. Individuals with Alzheimer’s disease also experience hallucinations, though to a […]
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Lewy Body Pathology – Not the First Problem Sign of Parkinson’s?

Lewy body pathology is found in the brains of 10 to 30% of older adults without any parkinsonian motor symptoms and is called incidental Lewy body disease (ILBD). Research suggests […]
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