Clinical Studies
RewinD-LB: A Phase 2b Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients with Dementia with Lewy Bodies (DLB)
What is this study about? DLB is characterized by progressive dementia, and fluctuating problems with memory and attention. Sleep disturbances, hallucinations, as well as tremors and problems with movement (called […]
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Study to Evaluate the Safety, Tolerability and Efficacy of CT1812 in Subjects With Mild to Moderate Dementia With Lewy Bodies (SHIMMER)
Dementia with Lewy bodies (DLB) is a progressive disorder affecting thinking, movement, behavior and sleep. Because currently there are no FDA-approved treatments for DLB, developing safe and effective treatments is […]
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CAMELOT Comparing Antipsychotic Medications in Lewy body disease Over Time
What is this study about? This study compares the effectiveness of the two most prescribed medications for the treatment of hallucinations in Parkinson’s Disease and dementia with Lewy bodies: quetiapine […]
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BEYONDD (Biomarker Evaluation in Young Onset Dementia from Diverse Populations)
What is this study about? Despite recent advances in understanding the biology of LBD and other causes of dementia, too little is known about how cognitive impairment develops in the […]
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Genetics studies in dementia with Lewy bodies
What is this study about? Investigators at the John P. Hussman Institute for Human Genomics (HIHG) want to understand the genetics of Lewy body dementia (LBD). Researchers hope to reduce […]
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Environmental and Reproductive Health Risk for Lewy Body Dementia (LBD – TOROS)
What is this study about? Lewy body dementia, including Parkinson’s disease dementia and dementia with Lewy bodies, can occur differently for women and men, although we are not sure why. […]
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Connect2Caregivers (C2C) Research Study
What is this study about? The Connect2Caregivers Research Study, an NIH funded research study, is being done to develop a unique matching process for caregivers of persons living with dementia, […]
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Evaluating A Diagnostic Test for Dementia with Lewy Bodies, the Syn-D Study
The Syn-D Study is a research study that aims to distinguish dementia with Lewy bodies (DLB) from Alzheimer’s disease in people at the early stages. This study may help advance […]
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Trial of Parkinson’s and Zoledronic Acid (TOPAZ)
What is this study about? People with neurodegenerative parkinsonism, including Lewy body dementia as well as Parkinson’s disease, multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal syndrome (CBS), […]
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Skin and Tissue Biomarker Study – Cleveland, OH
What is this study about? The purpose of this study is to study whether skin or tissue samples can be used to can distinguish Lewy body dementias from other types of dementia, and from control […]
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