Clinical Studies

Dementia with Lewy bodies (DLB) is a progressive disorder affecting thinking, movement, behavior and sleep. Because currently there are no FDA-approved treatments for DLB, developing safe and effective treatments is […]

The Synuclein-One Study (Syn-One) is a 500-patient, multicenter clinical study carried out by leading neurologists at academic centers across the U.S. The study aims to further validate the sensitivity and […]

What is this study about?  The purpose of this study is to study whether skin or tissue samples can be used to can distinguish Lewy body dementias from other types of dementia, and from control […]

Visual hallucinations are a common symptom of Lewy body dementias (LBD). But little is known about why hallucinations are so vivid in LBD compared to psychiatric disorders, or why they […]

LGBTQ adults with memory loss and other cognitive challenges face barriers to accessing healthcare, as well as a lack of culturally competent care. What is this study about? This study […]

Predicting ACcurately End-of-Life in Dementia with Lewy Bodies and Promoting Quality End-of-Life Experiences (PACE-DLB) This study will explore disease progression and care needs for persons with advanced dementia with Lewy […]

People with LBD present with different combinations of symptoms and severity, which can make diagnosis a challenge. Understanding whether one or more disease processes are underway may help diagnose and […]

People with LBD (including dementia with Lewy bodies and Parkinson’s disease dementia) experience life-altering changes in their cognitive abilities. This affects the quality of life for both the person with […]

What is this study about? The aim of this study is to develop better biomarkers for diagnosis and treatment of Lewy body disorders. In particular, there is a need to […]

What is this study about? The purpose of this study is to collect clinical information, brain imaging scans, and biological samples from people that have dementia with Lewy bodies. This […]