What is this study about?
The purpose of this study is to study whether skin or tissue samples can be used to can distinguish Lewy body dementias from other types of dementia, and from control participants who do not have dementia.
What is involved?
Participants will attend one study visit for a physical and neurological examination and assessment of their dementia symptoms. At a second visit participants will provide small skin samples, a nasal swabbing, or both. Participants who already require a colonoscopy unrelated to this study will have a small tissue sample taken from the colon as well.
Who can participate?
Individuals between 40-89 years of age, diagnosed with any of the following disorders:
- Dementia with Lewy bodies
- Parkinson’s disease (with or without dementia)
- Alzheimer’s disease
- Progressive supranuclear palsy
- Corticobasal degeneration.
Healthy adults with no neurological condition may also be eligible for this study.
University Hospitals Cleveland Medical Center and Case Western Reserve University School of Medicine
National Institute of Neurological Disorders and Stroke
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