The Synuclein-One Study (Syn-One) is a 500-patient, multicenter clinical study carried out by leading neurologists at academic centers across the U.S. The study aims to further validate the sensitivity and specificity of CND Life Sciences’ Syn-One Test to distinguish between the different types of synucleinopathies.
What is this study about?
Synuclein-One Study, an NIH funded research study strives to gather important data to help demonstrate the sensitivity and accuracy of the Syn-One Test. The Syn-One test looks for abnormal proteins inside the nerves in the skin. When this abnormal protein clumps it can cause problems in the way the central nervous system works. Scientists at CND Life Sciences have been working for more than 10 years to create the Syn-One Test to detect abnormal synuclein.
What’s involved?
Play an important role in advancing the science and application of the Syn-One test through participation in this one visit study that takes two hours to complete.
You will have an exam and provide medical history. You will complete questionnaires and a medical professional will take 3 small skin samples (called biopsies).
You will earn $50 for your full participation
Who can participate?
An individual may be able to take part in the study if he/she is either:
- Men or women 40-99 years old
- People with:
- Dementia with Lewy Bodies
- Multiple system atrophy
- Pure autonomic failure
You won’t be able to participate if you:
- Have heart disease
- Have had a stroke
- Are a current smoker or have a history of alcohol abuse disorder
- Use blood thinners (Plavix or aspirin is allowed, not both)
- Have a history of scarring or keloid formation
Study Sites
| Site Name, City | Contact Person | Contact details |
|---|---|---|
| MD First Research
Chandler, Arizona |
Sean Guardado
Colette Hairston |
(480) 508-1039, sguardado@brainandspineaz.com
(520) 524-5030 chairston@brainandspineaz.com |
| Movement Disorders Center of ArizonaPhoenix, Arizona | Susan Ortega
Danica Evidente |
(480) 526-5441 susan@movementdisorders.us
(480) 526-5441 danica@movementdisorders.us |
| The Neuro CenterCarlsbad, California | April Tenorio
Estela Soto |
(760) 732-0557 ext. 2135 april.tenorio@neurocenter.com (760) 732-0557 ext. 2123 estela.soto@neurocenter.com |
| Providence St. John’s HealthSanta Monica, California | Mini Gill | (213) 344-1963 mgill@pacificneuro.org |
| CenExel RMCR Clinical ResearchEnglewood, Colorado | Christine Stewart
Beth Capozzi |
(303) 867-5471 cstewart@kumarneuro.com
(303) 867-5468 bcapozzi@kumarneuro.com |
| Aventura NeurologyAventura, Florida | Jonathan Palmquist
Jose Macias |
(833) 732-2484 jpalmquist@visionaryinvestigators.com
(954) 243-5559 jmacias@visionaryinvestigators.com |
| Parkinson’s Disease and Movement Disorders Center of Boca RatonBoca Raton, Florida | Lauren Salmon | (561) 392-1818 ext. 2 |
| UF College of MedicineGainesville, Florida | Stephan Alvarez | (352) 733-2385 alvarez.stephan6@ufl.edu |
| Parkinson’s Disease Treatment Center SWFLPort Charlotte, Florida | Rachel Klasmeyer | (941) 743-4987 ext. 1 rachel@parkinsonsfl.com |
| NorthShore University Health SystemEvanston, Illinois | Lisette Garduno | (847) 503-4334 |
| Boston Medical CenterBoston, Massachusetts | Raymond James
Cathi Thomas |
(617) 638-7745 rcjames@bu.edu
(617) 638-7745 neurocat@bu.edu |
| Beth Israel Lahey HealthBoston, Massachusetts | Tanya Fennell | (781) 744-2862 tanya.l.fennell@lahey.org |
| Mayo Clinic RochesterRochester, Minnesota | Jade Gehrking
Jennifer Anderson |
(507) 266-0508 gehrking.jade@mayo.edu
(507) 284-2090 anderson.jennifer8@mayo.edu |
| NYU Medical Center New York, New York | Jose Martinez | (212) 263-7225 jose.martinez4@nyulangone.org |
| South Shore NeurologicPatchogue, New York | Kaitlyn Jaenicke | (631) 758-1910 ext. 2246 |
| Duke University Medical CenterDurham, North Carolina | Karen White | (919) 668-2905 |
| Providence Brain & Spine InstitutePortland, Oregon | Eliza Chow | (503) 216-8676 eliza.chow@providence.org |
| Vanderbilt University Medical CenterNashville, Tennessee | Katie Hay
James Silverman |
(615) 875-7403 kaitlyn.r.hay@vumc.org
(615) 875-5778 james.silverman@vumc.org |
| UT SouthwesternDallas, Texas | Amy Conger
Steve Hopkins |
(214) 648-0214 amy.conger@utsouthwestern.edu
(214) 648-9275 steve.hopkins@utsouthwestern.edu |
| Texas Movement Disorders SpecialistsGeorgetown, Texas | Wendy White | (512) 693-4041 ext. 6 |
| Evergreen HealthKirkland, Washington | Gowri Rajendran | (425) 899-5370 grajendran@evergreenhealthcare.org |
| Swedish Neuroscience ResearchSeattle, Washington | Katie Gelinas
Nathan Hansen |
(206) 320-4355 katharyn.gelinas@swedish.org
(206) 320-3542 nathan.hansen@swedish.org |
Study Sponsor
CND Life Sciences