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 Review article - treating delusions in LBD (w/Exelon, etc) 
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Joined: Fri Aug 11, 2006 1:46 pm
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Post Review article - treating delusions in LBD (w/Exelon, etc)
This abstract (just published) describes a review of studies done about treating delusions in DLB. The abstract and article mention one study in particular which looked at rivastigmine (Exelon). The "Mind, Mood, & Memory" booklet defines "delusions" as "fixed thoughts or ideas that are not based on reality." Delusions are not the same things as hallucinations. Delusions and hallucinations are both examples of "psychosis," or the loss of contact with reality.
Robin


Dementia and Geriatric Cognitive Disorders. 2007 Mar 15;23(5):307-311 [Epub ahead of print]

Treatment of Delusions in Dementia with Lewy Bodies - Response to Pharmacotherapy.

Fischer C, Bozanovic R, Atkins JH, Rourke SB.
St. Michael's Hospital, Toronto, Ont., Canada.

Background: Delusions are clinically important symptoms in dementia with Lewy bodies (DLB). The purpose of this review is to examine the level of evidence for treatment of delusions in DLB.

Methods: To achieve this objective Medline was searched. Studies were included in the review if they were prospective, separated delusions from hallucinations and were tested in patients with DLB.

Results: The review yielded a total of six studies. Although all studies showed effectiveness, only one study using rivastigmine had an adequate patient sample size and used a randomized controlled design.

Conclusion: Further studies are required before a definitive conclusion can be reached about effective treatments.

PubMed ID#: 17356274


Fri Mar 16, 2007 9:01 pm
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