Nelotanserin for Potential Treatment of Visual Hallucinations in LBD

What is this study about?

This trial is testing an experimental drug, nelotanserin, to determine if it is safe and effective in treating visual hallucinations in people with Lewy body dementia.

What is involved?

The study begins with a double-blind, placebo controlled phase, which means neither the researcher nor the person in the study will know who is getting the investigational medication, nelotanserin, or a placebo. Then, the study will continue with an open-label extension, in which all participants will receive the investigational medicine.

Participants in this study will attend an initial screening visit plus another 7 visits over approximately 18 weeks. Transportation assistance to and from study visits may be available.

Who can participate?

An individual with LBD may be able to take part in the trial if he/she:

  • Is between the ages of 50 and 85
  • Has been diagnosed with dementia with Lewy bodies (DLB) or Parkinson’s disease dementia (PDD)
  • Has frequent visual hallucinations

How can you learn more?

State City Study Contact Contact info
CA Fountain Valley Vickie Bounkousohn 714-378-5074
Boca Raton
Jamie Lovering 561-392-1818
FL Orlando Nadia Afghani 407-210-1316
Leigh Kreshal 913-827-4262
NC Chapel Hill Mallory Jolly 336-423-4192
NE Lincoln Kelly Espenschade

Chaitasi Majmudar

Gitti Janwatanagool



OH Cleveland Patricia Clark 216-445-9382
OH Columbus Jennifer Icenhour 614-293-6882
San Antonio
Sue Rafati 210-614-6000

Study Sponsor: 

Axovant Sciences, Ltd.

Still have questions?

For more information about this clinical trial, please contact Axovant Sciences at (919) 425-0709.