People with LBD present with different combinations of symptoms and severity, which can make diagnosis a challenge. Understanding whether one or more disease processes are underway may help diagnose and treat LBD more effectively.
What is this study about?
The aim of this study is to determine what features can help identify different sub-types of LBD. This includes studying the symptoms and using brain imaging to detect whether one or more disease process is unfolding in the brain.
What is involved?
This is an observational study in which participants will have annual clinical visits over several years. Participants will undergo clinical assessments, provide blood samples, and have MRI and PET scans.
Who can participate?
An individual may be able to take part in the study if he/she:
At least 55 years’ old
Is diagnosed with dementia with Lewy bodies (DLB) or Parkinson’s disease dementia (PDD)
Has the ability to agree to enter the study
Has a care partner who can attend all study visits
National Institutes of Health