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 Electroconvulsive therapy to treat two DLB patients 
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Joined: Fri Aug 11, 2006 1:46 pm
Posts: 4811
Location: SF Bay Area (Northern CA)
Post Electroconvulsive therapy to treat two DLB patients
This English-language abstract written by Japanese authors is a bit hard to understand.

These clinicians treat DLB patients as if they have "late catatonia." "Late catatonia" seems to be a psychiatric disorder that includes depression, anxiety, irritation, psychosis (hallucinations and delusions), and, finally, catatonia.

In two DLB patients with these symptoms, electroconvulsive therapy "proved to have a marked effect" while pharmacotherapy was ineffective.


Seishin Shinkeigaku Zasshi. 2011;113(2):144-56.

[Dementia with Lewy bodies (DLB) accompanied by symptoms of late catatonia: what to consider and how to treat].
[Article in Japanese]

Ueda S, Koyama K, Kocha H, Okubo Y.
Department of Neuropsychiatry, Nippon Medical School, Japan.

Dementia with Lewy bodies (DLB) has recently often been reported to exhibit various psychiatric symptoms. However, some DLB patients do not present typical clinical courses or psychiatric symptoms.

We report two DLB patients with characteristic psychiatric symptoms: a depressive state and anxiety in the early stage, and auditory hallucination, delusion of guilt, and catatonia in the later stage. Pharmacotherapy was ineffective, but electroconvulsive therapy proved to have a marked effect.

The clinical course represents the symptomatic concept of "late catatonia," which Sommer first reported in 1910 and Kocha later reappraised. In Japan, this has been prevailing as a useful concept in the field of clinical geriatric psychiatry.

We discuss what to consider and how to treat DLB patients including those with atypical courses and psychiatric symptoms. We consider and treated them as "late catatonia", with a favorable response to treatment. There is an important viewpoint which helps us understand the process. The viewpoint is to distinguish between "genera" and "types" of mental illnesses as inherited from classical psychopathology to modern psychiatry. DLB corresponds to "genera" and late catatonia to "types." In treating DLB patients with atypical symptoms and courses, it appears clinically very important to think more about late catatonia, exhibiting characteristic symptoms. This also reveals the usefulness of understanding and treating such cases based on the concept of "genera" and "types."

PubMed ID#: 2148553 (see for this English-language abstract only)

Thu Apr 14, 2011 7:24 pm

Joined: Wed Dec 30, 2009 1:46 pm
Posts: 3213
Location: WA
Post Re: Electroconvulsive therapy to treat two DLB patients
Interesting. I've read a little about using ECT for DLB and that there are some encouraging results.

Pat [68] married to Derek [84] for 38 years; husband dx PDD/LBD 2005, probably began 2002 or earlier; late stage and in a SNF as of January 2011. Hospitalized 11/2/2013 and discharged to home Hospice. Passed away at home on 11/9/2013.

Thu Apr 14, 2011 8:42 pm

Joined: Tue Aug 17, 2010 9:20 am
Posts: 184
Location: So Cal
Post Re: Electroconvulsive therapy to treat two DLB patients
I don't quite understand the lingo: at what stage is this beneficial? Thanks, Sher

Sher (53) married 29 years to Ken (66) who was diagnosed with LBD in 2008, but it most likely began many years before.

Thu Apr 14, 2011 11:54 pm

Joined: Fri Aug 11, 2006 1:46 pm
Posts: 4811
Location: SF Bay Area (Northern CA)
Post Re: Electroconvulsive therapy to treat two DLB patients
Hard to be sure since English is not their native language. But it seems that ECT was given in later stages of DLB.

Sat Apr 16, 2011 5:46 pm
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