View unanswered posts | View active topics It is currently Sun Dec 21, 2014 7:14 pm



Reply to topic  [ 4 posts ] 
 Sinemet shortage in early 2011? 
Author Message

Joined: Fri Aug 11, 2006 1:46 pm
Posts: 4811
Location: SF Bay Area (Northern CA)
Post Sinemet shortage in early 2011?
Those of you who take Sinemet may be interested in this news relayed by the National Parkinson's Foundation...

The "issue" with taking the generic form of Sinemet is that the FDA requires the bioequivalence of any generic product to be between 80% and 125% of that of the innovator product. This is a rather large range.


-------------
Email from National Parkinson's Foundation
1/7/11

Merck & Co. Inc. has informed the Parkinson's disease community that in early 2011, there may be a potential temporary supply shortage in the U.S. for SINEMET® (carbidopa-levodopa) and SINEMET CR® (carbidopa-levodopa controlled release tablets).

While there is currently no shortage, it is advisable to speak with your health care provider about appropriate steps should a shortage occur. Your health care provider can give you relevant information about potential short-term alternative therapies, including the availability of alternative generic equivalents.

The FDA has shown generic SINEMET® to be effective against the symptoms of Parkinson's disease, but dosing may need to be slightly adjusted due to differences in manufacturing and formulation. Should you need to temporarily switch to a generic version of SINEMET®, be aware that some people may experience a change in how the medication works. If you do experience a change, contact your health care provider who may prescribe a different dose or timing regimen.

Patients, caregivers and health care professionals in the U.S. who have more questions about the availability of SINEMET® can contact the Merck National Service Center at 1-800-NSC-MERCK.

NPF is committed to keeping you informed of developments on this issue. We will alert you if we get any more information about either a shortage developing or the crisis being averted. If you are informed by your doctor or pharmacist that SINEMET® is not available in your area, please contact us at 1-800-4PD-INFO (473-4636) or helpline@parkinson.org. If you have any questions, Dr. Okun is prepared to address issues about the shortage and generic substitution on our Ask the Doc online discussion forum.


Fri Jan 07, 2011 3:12 pm
Profile

Joined: Wed Oct 28, 2009 11:53 am
Posts: 969
Location: Ocala, FL
Post Re: Sinemet shortage in early 2011?
"...some people may experience a change in how the medication works."
....or doesn't always work, as the case may be...... :lol:

_________________
Leone Carroll (75); wife of Dale (75) who passed away March 23, 2011


Fri Jan 07, 2011 3:33 pm
Profile

Joined: Thu Dec 02, 2010 1:44 am
Posts: 93
Post Re: Sinemet shortage in early 2011?
Fran was taken off Sinemet, have a whole bottle not being used if there is a shortage. In fact I have many many LBD drugs in the house that Fran can't take. We have our own personal pharmacy. Although true, it is not to be taken literally. Bernie


Fri Jan 07, 2011 5:43 pm
Profile

Joined: Sat Jan 03, 2009 2:59 pm
Posts: 1978
Post Re: Sinemet shortage in early 2011?
Thanks for the information I have copied the # in case it should come up on the helplines ! I am sure it will at some point!

_________________
Irene Selak


Mon Jan 10, 2011 4:04 pm
Profile WWW
Display posts from previous:  Sort by  
Reply to topic   [ 4 posts ] 

You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot post attachments in this forum

Search for:
Jump to:  
Powered by phpBB © 2000, 2002, 2005, 2007 phpBB Group.
Designed by STSoftware for PTF.
Localized by Maël Soucaze © 2010 phpBB.fr