View unanswered posts | View active topics It is currently Tue Sep 16, 2014 7:37 pm



Reply to topic  [ 4 posts ] 
 LBD- Clinical; PSP- Pathological 
Author Message

Joined: Fri Aug 11, 2006 1:46 pm
Posts: 4811
Location: SF Bay Area (Northern CA)
Post LBD- Clinical; PSP- Pathological
Curiously there were two brain donation cases I was involved in this year where the clinical DX was Lewy Body Dementia but the pathological diagnosis was PSP (with nary a Lewy body to be found).

Actually, one case was PSP + AgD, and the other was AD + PSP.

Neither of these patients had hallucinations, which are not required for LBD but you have to have either hallucinations or fluctuating cognition.

In the PSP + AgD case, I know the diagnosing neurologist well and am very surprised. Her reply: "humbling."

Of course this made no difference for the treatment but always leaves people reeling in terms of expectations.


Wed Jan 06, 2010 11:51 pm
Profile

Joined: Fri Aug 11, 2006 1:46 pm
Posts: 4811
Location: SF Bay Area (Northern CA)
Post 
And another recent case was:
clinical DX = LBD
path DX = CBD and AgD

This gentleman had hallucinations but they've now been explained as being medication-related. He did NOT have fluctuating cognition.

And a fourth case (where the caregiver was a member here) was:
clinical DX = LBD
path DX = "atypical PSP"

I'm not sure if this gentleman had hallucinations or fluctuating cognition. I'd have to look back at the caregiver's posts.


Sun Apr 11, 2010 9:56 pm
Profile

Joined: Fri Jan 15, 2010 9:33 pm
Posts: 3359
Location: Vermont
Post 
What's AgD Robin, or anyone out there?


Sun Apr 11, 2010 10:01 pm
Profile

Joined: Fri Aug 11, 2006 1:46 pm
Posts: 4811
Location: SF Bay Area (Northern CA)
Post 
argyrophilic grain disease

It cannot be diagnosed during life as there's no diagnostic criteria for it. It's an age-related dementia.


Sun Apr 11, 2010 11:28 pm
Profile
Display posts from previous:  Sort by  
Reply to topic   [ 4 posts ] 

You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot post attachments in this forum

Search for:
Jump to:  
Powered by phpBB © 2000, 2002, 2005, 2007 phpBB Group.
Designed by STSoftware for PTF.
Localized by MaĆ«l Soucaze © 2010 phpBB.fr